实验室简介
本实验主要从事神经免疫疾病和神经退行性疾病的研究
NMOSD
Neuromyelitis optica (NMO) is an autoimmune inflammatory disease of the central nervous system that produces demyelinating lesions in spinal cord and optic nerve, and, to a lesser extent, in brain. Most NMO patients are seropositive for autoantibodies against aquaporin-4 (AQP4), a water-selective channel expressed in astrocytes throughout the central nervous system, as well as in epithelial cells in some peripheral organs including kidney and stomach [3]. Immunoglobulin G anti-AQP4 antibodies...