关俊宏实验室

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

2021

期刊 Cancer Cell

作者 Changzheng Lu · Junhong Guan · Steve Lu · Qihuang Jin · Benoit Rousseau · Tianshi Lu · Dennis Stephens · Hongyi Zhang · Jiankun Zhu · Mingming Yang · Zhenhua Ren · Yong Liang · Zhida Liu · Chuanhui Han · Longchao Liu · Xuezhi Cao · Anli Zhang · Jian Qiao · Kimberly Batten · Mingyi Chen · Diego H. Castrillon · Tao Wang · Bo Li · Luis A. Diaz · Guo-Min Li · Yang-Xin Fu

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

2021

期刊 Cancer Cell

作者 Junhong Guan · Changzheng Lu · Qihuang Jin · Huiming Lu · Xiang Chen · Lei Tian · Yanbin Zhang · Janice Ortega · Junqiu Zhang · Silvia Siteni · Mingyi Chen · Liya Gu · Jerry W. Shay · Anthony J. Davis · Zhijian J. Chen · Yang-Xin Fu · Guo-Min Li

NEDDylation regulates RAD18 ubiquitination and localization in response to oxidative DNA damage

2019

期刊 Biochemical and Biophysical Research Communications

作者 Junhong Guan · Xiaofeng Zheng

MyD88 NEDDylation negatively regulates MyD88-dependent NF-κB signaling through antagonizing its ubiquitination

2017

期刊 Biochemical and Biophysical Research Communications

作者 Fangxue Yan · Junhong Guan · Yanyan Peng · Xiaofeng Zheng

NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage

2017

期刊 Protein & Cell

作者 Junhong Guan · Shuyu Yu · Xiaofeng Zheng

The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen

2017

期刊 Journal of Biological Chemistry

作者 Xiaodong Dong · Junhong Guan · Chunfu Zheng · Xiaofeng Zheng

HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination

2014

期刊 Cell Death & Disease

作者 T. Li · J Guan · S. Li · X. Zhang · X. Zheng

RNF168-mediated H2A neddylation antagonizes its ubiquitination and regulates DNA damage repair

2014

期刊 Journal of Cell Science

作者 Tingting Li · Junhong Guan · Ziji Huang · Xiang Hu · Xiaofeng Zheng

A CRM1-Dependent Nuclear Export Signal Controls Nucleocytoplasmic Translocation of HSCARG, Which Regulates NF-κB Activity

2012

期刊 Traffic

作者 Mei Zhang · Bin Hu · Tingting Li · Yanyan Peng · Junhong Guan · Shenshen Lai · Xiaofeng Zheng

hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14

2012

期刊 Oncogene

作者 J. Zhang · D. Bai* · X. Ma · J Guan · X. Zheng

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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

NEDDylation regulates RAD18 ubiquitination and localization in response to oxidative DNA damage

MyD88 NEDDylation negatively regulates MyD88-dependent NF-κB signaling through antagonizing its ubiquitination

NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage

The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen

HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination

RNF168-mediated H2A neddylation antagonizes its ubiquitination and regulates DNA damage repair

A CRM1-Dependent Nuclear Export Signal Controls Nucleocytoplasmic Translocation of HSCARG, Which Regulates NF-κB Activity

hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14