#Wanli Liu*

A PIP2-derived amplification loop fuels the sustained initiation of B cell activation

Wanli Liu Lab , 清华大学

Growth of B cell receptor microclusters is regulated by PIP2 and PIP3 equilibrium and Dock2 recruitment and activation

Wanli Liu Lab , 清华大学

Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232

Wanli Liu Lab , 清华大学

Acidic phospholipids govern the enhanced activation of IgG-B cell receptor

Wanli Liu Lab , 清华大学

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

Wanli Liu Lab , 清华大学

The synaptic recruitment of lipid rafts is dependent on CD19-PI3K module and cytoskeleton remodeling molecules

Wanli Liu Lab , 清华大学

Substrate stiffness regulates B-cell activation, proliferation, class switch and T-cell-independent antibody responses in vivo

Wanli Liu Lab , 清华大学

A negative-feedback function of PKCβ in the formation and accumulation of signaling-active B cell receptor microclusters within B cell immunological synapse

Wanli Liu Lab , 清华大学

Through an ITIM-independent mechanism the FcgRIIB blocks B cell activation by disrupting the colocalized microclustering of the BCR and CD19

Wanli Liu Lab , 清华大学

B cell activation is regulated by the stiffness properties of the substrate presenting the antigens

Wanli Liu Lab , 清华大学

A new and robust method of tethering IgG surrogate antigens on lipid bilayer membranes to facilitate the TIRFM based live cell and single molecule imaging experiments

Wanli Liu Lab , 清华大学

The growth of B cell receptor microcluster is a universal response of B cells encountering antigens with different motion features

Wanli Liu Lab , 清华大学

PI(4,5)P2 determines the threshold of mechanical force–induced B cell activation

Wanli Liu Lab , 清华大学

PTEN-Regulated AID Transcription in Germinal Center B Cells Is Essential for the Class-Switch Recombination and IgG Antibody Responses

Wanli Liu Lab , 清华大学

MARCKS regulates tonic and chronic active B cell receptor signaling

Wanli Liu Lab , 清华大学

Profiling the origin, dynamics, and function of traction force in B cell activation

Wanli Liu Lab , 清华大学

An autoimmune disease variant of IgG1 modulates B-cell activation and differentiation

Wanli Liu Lab , 清华大学

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Wanli Liu Lab , 清华大学

Fc receptor–like 1 intrinsically recruits c-Abl to enhance B cell activation and function

Wanli Liu Lab , 清华大学

Traction force-mediated B cell activation: how and why

Wanli Liu Lab , 清华大学

Conformational change within the extracellular domain of B cell receptor in B cell activation upon antigen binding

Wanli Liu Lab , 清华大学

An Asia-specific variant of human IgG1 represses colorectal tumorigenesis by shaping the tumor microenvironment

Wanli Liu Lab , 清华大学

Farnesyl pyrophosphate is a new danger signal inducing acute cell death

Wanli Liu Lab , 清华大学

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