array(2) { ["lab"]=> string(3) "998" ["publication"]=> string(4) "8008" } Simple way to obtain pH-sensitive drug release from functional mesoporous silica materials - 郭伟实验室 | LabXing

郭伟实验室

简介 多功能纳米材料的制备及其光热转化性能研究

大学 哈尔滨师范大学 / 化学化工学院
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Simple way to obtain pH-sensitive drug release from functional mesoporous silica materials

2013
期刊 IET Nanobiotechnology
A novel pH-sensitive drug release system has been synthesised by functional mesoporous silica materials. SBA-15, calcium modified SBA-15 (Ca-SBA-15) and phosphate modified SBA-15 (PO4-SBA-15) were synthesised using solvent evaporation method. It is a simple and feasible way to prepare the doping mesoporous silica materials. They show the large surface are, high pore volume and uniform pore size. Metformin hydrochloride was used as the model drug, and the control release behaviour was investigated. The functional mesoporous silica materials show the pH sensitive drug release behaviour because of the adjustable interaction between the drug molecule and the host.

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