array(2) { ["lab"]=> string(3) "832" ["publication"]=> string(5) "12303" } Enhanced in situ detection and imaging of lipids in biological tissues by using 2,3-dicyanohydroquinone as a novel matrix for positive-ion MALDI-MS imaging - 新型多组学研究综合实验室（王晓东课题组） | LabXing

新型多组学研究综合实验室（王晓东课题组）

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大学 中央民族大学 / 生命与环境科学学院
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Enhanced in situ detection and imaging of lipids in biological tissues by using 2,3-dicyanohydroquinone as a novel matrix for positive-ion MALDI-MS imaging

2019
期刊 Chemical Communications
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A fluorescent dye, 2,3-dicyanohydroquinone (DCH), was optimized for use as a new matrix for positive-ion MALDI-MS imaging, and it provided enhanced lipid detection and imaging in biological tissues. The properties of DCH, include a strong ultraviolet absorption, low volatility in a high-vacuum (similar to 10(-7) mbar) source, super chemical stability, mu m-sized matrix crystals, uniform matrix deposition, and high ionization efficiency for the detection of lipids.

  • 卷 55
  • 期 83
  • 页码 12559-12562
  • Royal Society of Chemistry (RSC)
  • ISSN: 1359-7345
  • DOI: 10.1039/c9cc06961e
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