array(2) { ["lab"]=> string(4) "1381" ["publication"]=> string(5) "12204" } <i>In Situ</i> Imaging of Cancer Cell via Cancer Aptamer and its Fluorescent Clusters - 爱军个人主页 | LabXing

<i>In Situ</i> Imaging of Cancer Cell via Cancer Aptamer and its Fluorescent Clusters

2014
期刊 Advanced Materials Research
作者 Lu Ga · Jun Ai
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Silver nanoclusters synthesized using aptamer as matrices attracted more attention in the fields of medicine, pharmacology and biology. In this paper, we report a novel approach to sgc-8-C8-templated formation of fluorescent Ag nanoclusters and its application to bioimaging. This was further confirmed by flow cytometry. The cell toxicity (3-[4, 5-dimethylthiazolyl-2]-2, 5 -diphenyltetrazolium bromide, MTT) assay demonstrated that the silver nanoclusters has only little affect on the cytotoxicity to the cells. These results demonstrated that this aptamer-based method for labeling and imaging cellular protein is facile, effective.