One-pot solvothermal method to prepare functionalized Fe3O4 nanoparticles for bioseparation - Carbon4Energy

Surface functionalized magnetic nanoparticles were prepared by a facile one-pot solvothermal method in ethylene glycol solution. Zeta value, size, and magnetic properties could be well tuned by introducing different functional group molecules. Characterizations, including transmission electronic microscopy (TEM), scanning electronic microscopy (SEM), thermo-gravimetric analysis (TGA), X-ray powder diffraction (XRD) and vibrating-sample magnetometer (JSM-13), Fourier Transform Infrared Spectrophotometer (FT-IR) demonstrated the efficiency of this simple and general synthesis strategy. The hydrophilic magnetic nanoparticles with various surface functional groups and zeta values were evidenced an excellent candidate for bioseparation by extracting DNA molecules from a model mixture of cell fractures.