array(2) { ["lab"]=> string(4) "1034" ["publication"]=> string(4) "8530" } Unfolding the pathogenesis of systemic sclerosis through epigenomics - 肖瑛课题组 | LabXing

肖瑛课题组

简介 干细胞命运决定调控机制

大学 浙江大学 / 邵逸夫医院
关注
分享到

Unfolding the pathogenesis of systemic sclerosis through epigenomics

2020
期刊 STEMedicine
下载全文
As a group of autoimmune diseases, systemic sclerosis (scleroderma, SSc) is characterized by immune dysregulation, micro-vessels dominant obliteration, and the final fibrosis of the skin and or internal organs. Although the precise mechanisms are still unknown, increasing data shows that epigenetic mechanisms, such as DNA methylation, histone modification, and microRNA (miRNA), are strictly related to the pathogenesis of scleroderma. Epigenetic mechanisms, which can link genetics and environmental stress, represents a promising field in systemic sclerosis investigation. The objective of this review is, to sum up the current information about epigenetic alteration.

LabXing 上可以免费创建课题组网站
© LabXing 2018 关于LabXing 帮助中心 testing.service 京公网安备11010802025734号